1 Tau protein diffuses along the microtubule lattice
نویسندگان
چکیده
Background: Tau protein is believed to be stationary while bound to microtubules. Results: Tau molecules can diffuse along microtubules over distances up to several micrometers. Conclusion: Tau diffusion on microtubules is a novel mechanism for tau dispersion in cells. Significance: Modulation of tau binding and diffusion on microtubules by local modifications of microtubules can provide a tool to target tau to specific cellular compartments.
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